As an antigen-presenting cell, dendritic cells (DCs)have drawn great attention due to its powerful antigen-presenting ability and immunological regulation function. Recently, it is believed that DCs also participate in regulation of immune response: DCs can not only stimulate immune response, but also induce immune tolerance. This heterogeneity of DCs determines that they play very important role in the immune response in tumors, autoimmunity diseases and graft rejections.