Abstract:Objective:To isolate and identify phenolic glycosides and lignans from the rhizomes of Curculigo orchioides Gaertn.Methods: Phenolic glycosides and lignans were isolated by silica gel,Sephadex LH-20 chromatography and semi-preparative HPLC methods.The structures of the isolated compounds were identified by physiochemical and spectral analysis/Results: Five phenolic glycosides,one lignan and one sitosterol were isolated and identified from Curculigo orchioides Gaertn,namely, 2,6-dimethoxy benzolic acid(1),curculigoside A(2),curculigoside B(3),curculigine A(4),4-dichlorine-5-hydroxyl-3-methylphenol-1-O-β-D-glucopyranosyl-(1→6)-β-D-gluco-pyranosede(5),3,3′,5,5′-tetramethoxy-7,9′:7′,9 -diepoxylignan -4,4′-di-O-β-D-glucopyranoside(6),and β-sitosterol(7).Conclusion: Seven compounds have been isolated from Curculigo orchioides Gaertn; compound 5 is a new chlorine-containing phenol,and is named as curculigine D.