ObjectiveTo study the clinicopathologic properties of hippocampus glioma with temporal lobe epilepsy(TLE) as the main manifestation.MethodsThe clinical data of 6 patients with TLE and hippocampus masses were retrospectively analyzed.The 6 patients included 2 males and 4 females, with the longest history of epilepsy being 4 years.ResultsAll the 6 patients were surgically treated and were pathologically confirmed to have gliomas,including one angiocentric glioma(AG),one pilocytic astrocytoma(PA) with mucous degeneration,one astrocytoma,one oligoastrocytomao,one oligodendroglioma and one glioblastoma.Glial fibrillary acidic protein(GFAP) was strongly positive in all cases.Epilepsy disappeared after surgery in 5 cases; one patient had recurrence and received a second operation.ConclusionHippocampus gliomas with TLE as the main manifestation are usually low-grade gliomas of various types,and operation can obtain satisfactory prognosis.