ObjectiveTo use numerical simulation for analying hemodynamic changes in intracranial aneurysm with elastic wall, and to analyze the effect of mechanical properties of the aneurysm wall on the hemodynamic changes.MethodsBased on the DSA images of a patient with multi-intracranial aneurysm, the numerical simulation of the hemodynamics of the elastic intracinal aneurysm was processed using a software of finite element method of computational fluid dynamics(CFD) and the computational fluid-structure interaction analyses. We also investigated the effect of the coupling of hemodynamics and aneurysm wall movement.ResultsThe morphology of the elastic aneurysm underwent deformation, and the angle between aneurysm and parent artery also changed, affecting the inflow jet dispersed into the flow field of aneurysm and the distribution of wall shear stress on the surface of aneurysm.Conclusion The numerical simulation of CFD can directly reflect the hemodynamic characteristics of aneurysms. More accurate elastic wall aneurysm model is needed to improve the quantitative analysis of the hemodynamics of intracranial aneurysms.