The green fluorescent protein (GFP) is a bioluminescent protein derived from the Jellyfish Aequorea．As a reporter gene, GFP has been used in a variety of biological researches. A large proportion of the clinical fungal infections are caused by Candida albicans, making it very important for further study. GFP has also been widely used in Candida albicans-related studies. The fusion genes harboring GFP gene can yield expression of the fusion protein, which can emit green fluorescence and can be used for gene expression and protein localization. This paper reviews the application of GFP in the Candida albicans-related studies.