Obesity is the most important risk factor of primary hypertension.Rapid increase of obesityrelated hypertension has become a worldwide problem. But the specific mechanism of the condition remains to be fully understood. This paper reviews the latest literatures and tries to explain the mechanism of obesityrelated hypertension from the following four aspects:hypoadiponectinemia, leptin and resistance of leptin, insulin and resistance of insulin and the activation of reninangiotensin system(RAS).