tive To evaluate the value of intraductal ultrasonography (IDUS) in diagnosis of pancreatic diseases.MethodsWe retrospectively reviewed the imaging data of 63 patients with pancreatic diseases who underwent IDUS from February 2005 to February 2010.A 20 MHz over-the-guidewire intraductal US catheter probe was used during endoscopic retrograde cholangio-pancreatography(ERCP) for further examination of the pancreas.We also compared the results of CT, magnetic resonance imaging (MRI), endoscopic ultrasonography (EUS) and abdominal ultrasonography in diagnosis of pancreatic diseases, so as to further evaluate the value of IDUS in the clinical diagnosis of pancreatic diseases.ResultsThe accuracies of IDUS in diagnosis of chronic pancreatitis (23 cases), pancreatic cancer (10 cases), intraductal papillary mucinous tumors (IPMT, 25 cases), and pancreatic adenoma (4 cases) were 93.7% (59/63), 100.0% (63/63), 90.5% (57/63), and 96.8% (61/63), and the Kappa values were 0.854, 1.00, 0.898, and 0.848, respectively.The diagnostic accuracies and Kappa test values of IDUS were better than those of the other four methods.IDUS correctly diagnosed the pancreatic cystadenocarcinoma in one patient before operation.ConclusionIDUS has a high diagnostic value for pancreatic diseases.