ObjectiveTo evaluate the clinical effects of Aquacel-Ag dressing in treatment of pediatric superficial Ⅱ burn wound. MethodsForty patients fulfilling the inclusion criteria were included in the present study. Two burn wound areas of similar size were selected from each patient and were randomly divided into two groups. The burn areas in the control group were covered with SD-Ag and those in the treatment group were managed with Aquacel-Ag dressing. The healing time, recovering rate, seepage amount, the frequency of dressing changes and frequency of changing the inner most layer gauze were compared between the two groups. Meanwhile, the laboratory abnormalities and adverse effect were closely monitered during the treatment. ResultsCompared with the SD-Ag group, the Aquacel-Ag dressing group exhibited a significantly shorter healing time (P＜0.05); it also had higher recovering rates (P＜0.05, P＜0.01) on the 3rd, 7th and 14th day after treatment; moreover, Aquacel-Ag dressing also resulted in significantly lower seepage amount and reduced dressing changes (P＜0.01). However, the outcomes of bacterial culture were not significantly different between the two groups (P＞0.05). We also found there was no direct relationship between the laboratory abnormalities and the therapeutic measures during the study, and most patients had no uncomfortable chief complaint. ConclusionAquacel-Ag dressing can shorten the healing time, improve healing rate, reduce seepage amount, and decrease frequency of dressing change for superficial Ⅱ burn wound in pediatric patients. And it has an antimicrobial property similar to SD-Ag for superficial Ⅱ burn wound and shows no noticeable adverse effect.