Hypertension disorder complicating pregnancy (HDCP) can be associated with multiple organ dysfunction or failure, even convulsions, coma and death in severe cases. HDCP poses a serious threat to maternal and fetal health, and is one of the important reasons for maternal and perinatal infant mortality. However, the etiology of HDCP remains largely unknown. Recently many studies have found HDCP is accompanied by changes of some hormones, including progesterone, human chorionic gonadotropin, thyroid hormone and corticotropin-releasing hormone. In this review we delineated the fluctuations of the above four common hormones in HDCP patients and their relation with HDCP, hoping to cast new sights for its etiology and prediction.