[Abstract] Objective To study the discharge change of CA1 place cell after hippocampal formation（HF）accepting the visual-vestibular-proprioceptive mismatch configuration as a match by learning, which could provide new scientific experimental data for revealing the fact that HF may encode any combination of sensory inputs. Methods The visual-vestibular-proprioceptive mismatch configuration was set up. According to theta rhythm recording and theta power calculation in rat hippocampal dentate gyrus, it was acquainted that the rat had been adaptive to the sensory conflict. The assembly discharge of CA1 area place cell was recorded in awake rat by using extracellular tungsten microelectrode record and stereotaxic techniques after the rat adapted to sensory mismatch. Results Out of 56 place cells, 14 showed consistent spatial firing in both the match and mismatch condition (both translocation-related experience-independent neurons). 33 showed different spatial firings across the sessions (both translocation-related experience-dependent neurons). The mean sizes of the place fields were larger in both translocation-related neurons than that of experience-dependent neurons. The firing rate distributions in the place fields were negatively skewed and asymmetric. Conclusion The HF encodes a naturally impossible new configuration of sensory inputs after adaptation, the HF is capable of updating it stored memory to accept a new configuration as a match. The HF may encode any combination of sensory inputs.