Objective To discuss the nursing interventions of patients with confirmed Ebola virus disease. Methods and Results We retrospectively analyzed the nursing method and experience of 4 confirmed cases with Ebola virus disease in Chinese Ebola Treatment Unit, which was established by Chinese People's Liberation Army medical team in Liberia. Following the strict personal protective process, we provided timely symptomatic care, seamless psychological care, carefully basic care and comprehensive health education for the patients. We also timely summarized our experience of nursing interventions. Through dedicated treatment and nursing, despite 1 case died, 3 cases were cured and discharged. Conclusion Since there have been no specific and effective medications for Ebola virus disease by now, timely and correct symptomatic treatment and dedicated nursing with high efficiency are of great significance for patients to fight against with Ebola virus disease and regain their health.