Endometriosis is a common gynecological disorder of the reproductive age, and in recent years there is an increasing tendency in its incidence. Classical theories have failed to fully explain the exact pathogenesis of endometriosis. Previous studies have found the imbalance of oxidation system and antioxidant system and increased oxidation markers in patients with endometriosis, and it has also been found that antioxidants have prevention and treatment effects for endometriosis. All the above suggests that endometriosis is associated with oxidative stress. This article reviewed the correlation of endometriosis with oxidative stress, so as to provide reference for exploring the pathogenesis and possible antioxidant therapy of endometriosis.