Objectives: The aim was to investigate the clinical features, treatments and prognosis of non- urothelial carcinoma of urinary bladder. Materials and Methods: A total of 31 patients with non-transitional bladder cancer from June 2009 and April 2015 in our hospital were retrospectively evaluated in this study, of whom 26 males and 5 females, aged from 31 to 84 years, average age was 61 years. The patients’ characteristics, including symptoms, tumor number, size, and localization, pathological types before and after the operation, treatments, recurrence and survival rates were all follow up and recorded. Results: 77.4% of the preliminary symptoms among these 31 patients were gross hematuresis, Tumor most commonly located in left or right lateral wall of bladder. Mono-tumor and multi-tumor in the bladder have similar proportion. There are 20 cases of tumors larger than 3cm, accounted for 64.5%. 18 patients underwent radical cystectomy，4 patients underwent partial cystectomy ,6 patients underwent transurethral resection of bladder tumor and 3 patients gave up operation. Of these tumors, 16(51.6%) were cases of adenocarcinoma, 8 (25.8%) squamous cell carcinoma ,3 sarcoma,2 small cell carcinoma , 2 adenosquamous. 29 patients were followed up for 2 to 62 months(2 cases were lost to follow-up)．Median survival for adenocarcinoma patients is 23m, squamous cell carcinoma patients is 15m, andother histological types is 26m. Median survival for patients treated by radical cystectomy is 24m, higher than 20m of others. Conclusion: Non- urothelial carcinoma of the urinary bladder, with the most commom preliminary symptoms of gross hematuresis, located mostly in left or right lateral wall of bladder, and the size of the tumors were often larger. Prognosis of urinary bladder tumors was directly related to histological type and therapy method. The effect of chemotherapy and radiation is limited. Early radical cystectomy should be performed to improve prognosis.