Objective To synthesize fully protected p-methoxyphenyl D-galactopyranosyl(α1→4)-(D-galactopyranosyl)-(β1→3)-2-deoxy-2-acetamido-D-glucopyranoside. Methods With D-galactose and D-glucosamine hydrochloride used as the initial compounds, we stereoselectively and efficiently synthesized p-methoxyphenyl 2,3,4,6-tetra-O-acetyl-D-galactopyranosyl (α1→4)-(2,3,4,6-tetra-O-benzyl-D-galactopyranosyl)-(β1→3)-6-benzyl-2-deoxy-2-acetamido-β-D-glucopyranoside (1) by glucosinolates glycosylation and Schmidt glycosylation. Results Our method efficiently produced the target compound, and the structures of the main intermediates and target compound were confirmed by ¹HMNR, ¹³CMNR and MS. Conclusion We have established a simple synthesis method with high universal property for target compound; additionally, the protective base is easily removable. Our method is applicable for the synthesis of various oligosaccharides.