Thyroid associated ophthalmopathy (TAO) is a common autoimmune ophthalmic disease, which often triggers a series of ocular surface diseases, such as xerophthalmia, exposure keratitis and so on. A large number of researches have been done on serious problems such as exposure keratitis by researchers in and outside China, while report on xerophthalmia caused by TAO is scarce, leading to difficulties for comprehensive assessment of patients' condition. This review summarized the effects of various TAO therapeutic regimens on ocular surface.