Objective To explore the role of a comprehensive teaching method based on a diagnosis-and-treatment simulator for bronchoscopic procedure in the training of high-frequency electrocautery using snare. Methods A prospective self-control study including 20 trainees from the Bronchoscopic Center of Changhai Hospital was designed to evaluate the training outcome of bronchoscopic high-frequency electrocautery snare technique. During the training course, theoretical knowledge teaching was followed by simulator-based practice under the guidance of respiratory endoscopic exports from Changhai Hospital. We recorded and analyzed the procedure accuracy and fluency,operation time, and target tissue excision rate of each trainee before and after the training project. The appraisal of the training effect for each trainee in this study was conducted by questionnaire survey. Results All the 20 trainees successfully completed the whole training project. Compared with the data before the training, the procedure accuracy of excising the target tissue by snare after the training was significantly increased from 5.73±1.37 to 8.50±0.81 (P<0.01); the fluency of operating snare was significantly improved from 5.20±1.61 to 8.27±1.00 (P<0.01); the total operation time-consuming was significantly shortened from (214.9±112.6)s to (88.1±18.2) s (P=0.01); and the target tissue excision rate was increased significantly from (60.0±16.3)% to (76.0±12.6)% (P=0.05). The questionnaire survey showed that all the trainees benefited from the comprehensive simulator-based teaching method. The advantages of this teaching method included repeatability, high simulation degree, safety, operational stability and improved training efficiency. Conclusion The simulator-based comprehensive teaching method has a distinct teaching outcome in bronchoscopic electrocautery snare technique training, and is worth promoting in bronchoscopic training.