Abstract: Objectives: This article tries to realize the impact of liver trauma and iatrogenic invasive examination on liver and body through 1 rare clinical case report of hepatic artery portal venous fistula (HAPF). Methods：We combined the data of 19 years after live rupture repair operation which was caused by juvenile trauma with the domestic and foreign literatures to analyzed the cause and the present situation of diagnosis and treatment. Conclusions: Traumatic and iatrogenic hepatic artery portal vein fistula is rare at home and abroad, we explored etiology and diagnosis by high resolution three-dimensional reconstruction of CT and 3D vascular reconstruction technology in the paper. Then, we suspect that it was arterial-portal venous shunt which caused by trauma contributes to portal hypertension, and we conclude that all liver trauma and invasive procedure may result in HAPF. Furthermore, we suggest that the HAPF should be clearly classified as one of complications in liver trauma and iatrogenic invasive procedures. Finally，we learned that neither one of acute renal failure, acute liver failure and acute heart failure is a rare clinical presentation of HAPF.