Objective To explore the characteristics of spinopelvic sagittal parameters in degenerative lumbar spondylolisthesis patients and the relationship between these parameters and lumbar spondylolisthesis. Methods From Jun. 2016 to Jun. 2018, 42 patients with degenerative lumbar spondylolisthesis (DLS) were enrolled in study group, and 58 degenerative lumbar disease patients without spondylolisthesis were enrolled in control group. The general characteristics of the patients were collected. The sagittal parameters, including pelvic tilt (PT), pelvic incidence (PI), sacral slope (SS), thoracic kyphosis (TK), thoracolumbar kyphosis (TLK), lumbar lordosis (LL) and sagittal vertical axis (SVA), were measured on lateral X-ray films of full-length spine. The differences of general characteristics and sagittal parameters were compared between the two groups. With the lumbar spondylolisthesis rate as dependent variable and the spinopelvic sagittal parameter as independent variable, logistic regression model was used to analyze the risk factors of lumbar spondylolisthesis. Results There were no significant differences in the age, gender, height or body mass of the patients between the two groups (all P>0.05). There were significant differences in the PT, PI, SS, LL, TLK and SVA between the DLS group and the control group (all P<0.05), but there was no significant difference in the TK (P>0.05). Logistic regression analysis showed that LL and PT were risk factors of lumbar spondylolisthesis (both P<0.05). Conclusion The sagittal parameters (PT, PI, SS, LL, TLK and SVA) in the patients with DLS are significantly changed. LL and PT are the risk factors of lumbar spondylolisthesis.