Portal vein aneurysms (PVA) are a rare vascular anomaly of the portal system, Pseudoportal vein aneurysms complicated to laparoscopic cholecystectomy(LC) are much less encountered. If a pseudoportal vein aneurysm was misdiagnosed as a focal abscess at gallbladder fossa on base of the clinical manifestations and imaging findings after LC, it is readily for the surgeon to make a therapeutic decision to take ultrasound-guided catheterization and drainage against the gallbladder fossa abscess, however, which can cause a life-threatening bleeding. In this paper, we reported the experience of successful rescue of one patient who faced life-threatening bleeding from a pseudoportal vein aneurysm, which was complicated to a laparoscopic cholecystectomy procedure and was managed by ultrasound-guided puncture and drainage treatment. We described the possible mechanism of the formation of pseudoportal vein aneurysm after laparoscopic cholecystectomy and the causes of misdiagnosis of pseudoportal vein aneurysm by ultrasonography and MRI. We also intend to share our experience how to appropriately manage the emergency in face of bleeding while the aneurysm has been punctured.