The biphasic calcium phosphate material is the golden standard alternative materials in bone reconstruction operation. It is mostly from artificially synthesized, but the method is featured by intricate preparation process, uncontrollable pore size distribution, high cost, and low biological activity. Some researches have found that marine fish bone, as a natural bone source, can also be used to prepare biphasic calcium phosphate materials. With a wide range of sources, simple preparation methods and high content of β-tricalcium phosphate, it retains the natural microscopic pore structure, making it a potential bone replacement support material. In this paper, the research progress on biphasic calcium phosphate material from marine fish bone is reviewed regarding preparation methods and material characterization.