Since December 2019, many cases of pneumonia of unknown causes have been found in Wuhan and surrounding areas of Hubei Province, China. With the aggravation of the epidemic, on January 24, 2020, medical team of Naval Medical University (Second Military Medical University) in Wuhan started emergency medical rescue. This medical rescue was not only a treatment war, but also an antiepidemic war. It is very important to have strict personal protection, disinfection and isolation measures and epidemic prevention in the camp, which are the precondition and guarantee to ensure zero infection of medical staff. In this paper, we introduce our measures and experience on epidemic prevention and infection control, such as personnel management and decontamination.