Myofascial pain syndrome is a common clinical local pain syndrome with high incidence, and there is no radical treatment at present. As a safe, non-invasive and non-pharmacological therapy, exercise therapy plays an important role in the treatment of this disease. Exercise therapy includes active exercise (aerobic exercise, stretching exercise, myofascial self-release training), passive exercise (manual compression, device assistance, intramuscular effect sticking), traditional Chinese medicine exercise, and comprehensive therapy. This article reviews the clinical research progress of exercise therapy in the treatment of myofascial pain syndrome.