Objective To explore the safety and efficacy of endovascular interventional therapy for traumatic internal carotid artery dissection (TICAD). Methods Sixteen patients with TICAD confirmed by digital subtraction angiography (DSA), who received endovascular interventional therapy in the Stroke Center of Changhai Hospital of Naval Medical University (Second Military Medical University) from Jan. 2014 to Nov. 2019 and followed up for at least 6 months, were retrospectively included. The general characteristics, immediate postoperative outcomes, perioperative complications, and clinical and imaging follow-up data were analyzed. Results There were 14 males and 2 females with a median age of 37 years (range, 16-63 years). The causes of TICAD included traffic accident (11 cases), boxing (1 case), falling (1 case), neck sprain (1 case), high-pressure water gunshot (1 case) and high falling (1 case). Preoperative imaging examination showed internal carotid artery dissecting aneurysms in 14 patients, including 1 patient with 2 dissecting aneurysms. Of the 15 dissecting aneurysms, 5 were treated with flow diverter, 8 with stent-assisted coil embolization, 1 with balloon-assisted coil embolization, and 1 with simple stent implantation. Immediate postoperative angiography showed that 7 dissecting aneurysms were completed occluded, 1 had residual contrast agent in aneurysm neck, and 7 had residual contrast agent in aneurysm body. Two patients, with imaging examination showing simple internal carotid artery dissection, received simple stent implantation and had resumed blood flow immediately after operation. No operation-related complications developed in the 16 patients. During the clinical follow-up, the Glasgow outcome scale (GOS) score was 5 in 15 patients, and 3 in 1 patient. The follow-up imaging results of 14 patients showed that 13 of them were cured, and 1 was improved. Conclusion Endovascular treatment is safe for TICAD and can effectively improve the clinical prognosis of the patients, but this conclusion needs to be confirmed by large-scale prospective clinical trials.