Objective To evaluate the effectiveness of dorsal bridge plating combined with Kirschner wire elastic fixation in the treatment of Myerson type B Lisfranc injury. Methods The clinical data of 16 patients with Lisfranc injury who underwent surgical treatment in Department of Orthopaedics, Baoshan Luodian Hospital and Department of Orthopaedics Trauma, The First Affiliated Hospital of Naval Medical University (Second Military Medical University) from Jun. 2018 to Dec. 2020 were collected. There were 10 males and 6 females with an average age of (44.5±12.1) years (range 25-65 years). There were 9 cases of left foot injury and 7 cases of right foot injury. The time from injury to operation was (7.5±1.7) d (range 5-11 d). According to the Myerson classification, all cases were type B. The second tarsometatarsal joint was fixed with dorsal bridge plating, and the dorsal ligament was also repaired. Furthermore, the medial and lateral columns were fixed with Kirschner wire. The wound healing was observed and the complications were recorded. At the final follow-up, the effectiveness and function were assessed by American Orthopaedic Foot and Ankle Society ankle-hindfoot scale (AOFAS-AHS), and the pain condition was assessed by visual analogue scale (VAS). Results All patients were followed for up 12-20 months, with an average of (17.2±2.2) months. All the incisions healed by the first intention. No incision infection, skin necrosis, osteofascial compartment syndrome, deep peroneal nerve injury, lower extremity deep venous thrombosis, Kirschner wire migration, internal fixation failure or traumatic osteoarthritis were observed in any patients. At the last follow-up, the AOFAS-AHS score was 86.3±3.4 (range 70-95), including excellent in 10 cases, good in 4 cases, and fair in 2 cases, with an excellent and good rate of 87.5% (14/16); the VAS score was 1.7±0.9 (range 1-4). Conclusion For patients with Myerson type B Lisfranc injury, the treatment of rigid fixation of the second tarsometatarsal joint with dorsal bridge plating, repair of the dorsal ligament, and elastic fixation of the medial and lateral columns with Kirschner wire can obtain satisfactory clinical results.