Mechanical thrombectomy is an effective treatment for patients with acute ischemic stroke (AIS) due to large vessel occlusion, but more than half of the patients have poor clinical prognosis. The transformation of intracranial hemorrhage caused by postoperative high perfusion is closely related to the deterioration of clinical prognosis after AIS mechanical thrombectomy, and low perfusion may lead to further aggravation of infarction. Therefore, strengthening postoperative blood pressure management and balancing the risks of intracranial high perfusion and low perfusion are of great significance for improving patient prognosis. ENCHANTED2/MT research is to explore the effect of intensive antihypertensive therapy after mechanical thrombectomy, and it immediately attracts widespread attention in the field of cerebrovascular diseases at home and abroad. This article summarizes the most important research in the field of cerebrovascular diseases, and interprets the research progress in blood pressure management after AIS mechanical thrombectomy.