Objective： To study the antifungal activity of the new triazole compounds against candida species. Methods: The MICs of new triazole compounds were determined in in vitro antifungal tests to evaluate the activities of title compounds. Results: All new triazole compounds had activity against candida species, especially high activity against candida albicans. Compound 12 exhibited remarkably high efficacy and was 256 times more active than fluconazole against candida albicans. Compound 17 was the most effective agent against fluconazole-resistant candida albicans and was 16 times more active than fluconazole. Conclusion: The 2 compounds are worth advanced studying as potential drugs.