| 摘要: |
| 目的：研究乳腺癌患者局部扩大切除术中切缘宽度与生存率、局部复发率和术后乳房美容效果之间的关系。方法：回顾了我院42例行切缘宽度为2 cm的局部扩大切除术的病例和37例行切缘宽度为3 cm的局部扩大切除术的病例,计算并比较两组病例治疗后5年生存率、10年生存率、5年复发率、10年复发率和术后乳房的美容效果。结果：两组病例在5年生存率、10年生存率、5年局部复发率及10年局部复发率均无统计学差异。在美容效果上,评分优良率2 cm组（90.5%）要优于3 cm组（73.0%）,两者存在统计学差异（P<0.05）。结论：行局部扩大切除术时,切缘宽度2 cm已基本足够,无需进一步扩大切缘宽度,否则可能会降低术后乳房美容效果。 |
| 关键词: 乳腺肿瘤 保留乳房手术 切缘宽度 对比研究 |
| DOI：10.3724/SP.J.1008.2007.01229 |
| 投稿时间：2007-04-16 |
| 基金项目: |
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| Breast conserving operation for breast cancer with 2 cm and 3 cm incision margins: a comparison of outcomes |
| YU Yue,SHI Jun-yi*,SHENG Yuan,LI Li,HU Wei |
| (Department of General Surgery,Changhai Hospital,Second Military Medical University,Shanghai 200433,China) |
| Abstract: |
| Objective：To explore the relationship between margin width in extended lumpectomy for breast cancer with survival rate, local recurrence rate,and cosmetic result.Methods: The clinical data of 42 breast cancer patients who had a 2 cm incision margin width (group A) and 37 who had a 3cm incision margin width (group B) were retrospectively analyzed. The 5year, 10year survival rates, recurrence rates, and the cosmetic results were compared between the 2 groups. Results: The 5year and 10year survival rates in patients of group A were 90.1% and 85.3%, respectively; in patients of group B were 92.3% and 83.6%, respectively（P>0.05）. The 5year and 10year local recurrence rates in patients of group A were 5.9% and 11.6%, respectively; in patients of group B were 3.4% and 12.9%, respectively（P>0.05）.The cosmetic result was significantly better in group A than that in group B（P<0.05）.Conclusion: An incision margin width of 2 cm is enough for extended lumpectomy. It is not necessary to further expand the margin width; otherwise, it may influence the cosmetic results after operation. |
| Key words: breast neoplasms breast conserving operation incision margin comparative study |
