| 摘要: |
| 目的：应用速度向量成像(VVI)技术，探讨肥厚型心肌病（HCM）患者左室心肌收缩期应变（ε）、应变率（SR）的改变。方法：选取20例室间隔肥厚的HCM患者和20例年龄配对的健康志愿者，在VVI模式下，分别取心尖四腔、三腔和二腔切面，分析左室18个室壁节段的ε和SR曲线，测量收缩期峰值。结果：对照组左室心肌收缩期SR值为(-1.06±0.09)/s，HCM组为(-0.74±0.16)/s，HCM组左室心肌各节段收缩期SR较对照组明显减低，差异有统计学意义（P<0.05）。HCM组各节段收缩期SR减低不仅仅限于肥厚部位，也存在于非肥厚部位。结论：HCM患者左室心肌收缩期ε和SR明显低于对照组，HCM患者收缩期ε和SR的减低不仅限于肥厚部位。 |
| 关键词: 肥厚型心肌病 速度向量成像 应变 应变率；左心室；心肌收缩期 |
| DOI：10.3724/SP.J.1008.2008.00390 |
| 投稿时间：2007-10-15修订日期：2008-03-11 |
| 基金项目: |
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| Quantitative analysis of left ventricular systolic strain and strain rate in hypertrophic cardiomyopathy patients by velocity vector imaging |
| JIANG Hong*,ZHI Guang,YAN Guo-hui,HOU Hai-jun,ZHOU Xiao,XU Yong |
| (PLA Postgraduate Medical School,Beijing 10000,China) |
| Abstract: |
| Objective：To observe the changes of left ventricular (LV) systolic strain(ε) and strain rate(SR) in patients with hypertrophic cardiomyopathy (HCM) and normal healthy subjects by velocity vector imaging(VVI).Methods: Twenty patients with HCM and 20 age-matched healthy adults were enrolled in this study. The peak systolic ε , SR of 18 segments in the 4, 3 and 2-chamber views were measured by VVI. Results: It was found that the systolic SR was (-1.06±0.09)/s in the healthy control group and (-0.74±0.16)/s in the HCM group（P<0.05）. The reduction of systolic SR in HCM group was found not only at the hypertrophic regions but also at normal regions. Conclusion: The systolic ε and SR in HCM group is lower than that in the normal control group. The reduction of systolic ε and SR in HCM group is not limited to the hypertrophic region. |
| Key words: hypertrophic cardiomyopathy velocity vector imaging strain strain rate left ventricle systole |
