| 摘要: |
| 临床上目前主要基于治疗前后的形态学改变评价肿瘤治疗疗效，用于早期预测和评估肿瘤治疗疗效的能力非常有限。功能和分子磁共振成像（MRI）既能反映肿瘤的某些功能状态和分子生物学的信息，又能提供优质的解剖信号，可以用于早期预测和评价肿瘤的疗效。 |
| 关键词: 磁共振成像 肿瘤 治疗结果 |
| DOI：10.3724/SP.J.1008.2008.00979 |
| 投稿时间：2007-10-19修订日期：2008-06-23 |
| 基金项目:国家自然基金（30470513、30570534），上海市科委资助课题（0552nm026、06DZ19503）. |
|
| Functional and molecular MR imaging in evaluating outcomes of tumor therapy |
| YUAN Zheng,LIU Shi-yuan*,XIAO Xiang-sheng |
| (Department of Radiology,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China) |
| Abstract: |
| The evaluation of outcomes of cancer therapy in clinic are largely based on volumetric and morphological evidences.These evidences,however,are very limited in assessing the early effects of therapy.Functional and molecular MR imaging allows co-registration of functional/molecular-based information with high-resolution anatomical detail within the same imaging modality，which makes it possible for assessing the early effects of tumor therapy. |
| Key words: magnetic resonance imaging neoplasms treatment outcome |
