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粪便脱落细胞检测应用于大肠癌筛查的研究进展
陈燕,李兆申*,蔡全才,郭爱珍
0
(第二军医大学长海医院消化内科,上海 200433)
摘要:
我国大肠癌发病率呈逐年上升趋势,筛查可以有效降低其发病率和病死率。然而,目前常用的大肠癌筛查手段尚存在明显缺陷。粪便脱落细胞检测具有早期发现病变、无创、患者依从性好等优点,在大肠癌筛查上具有潜在的应用前景,本文就这方面研究进展作一综述。
关键词:  结直肠肿瘤  筛查  大肠脱落细胞检测
DOI:10.3724/SP.J.1008.2007.01120
基金项目:国家自然科学基金(30771838).
Exfoliated cells from human stool for screening of colorectal cancer:a progress
CHEN Yan, LI Zhaoshen*, CAI Quancai, GUO Aizhen
(Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China)
Abstract:
The morbidity of colorectal cancer has been increasing year by year in China.Screening test of colorectal cancer can effectively decrease the morbidity and mortality of it.However, the current screening technique has obvious defect.Screening of exfoliated colonocytes isolated from human stool for early detection of colorectal cancer is noninvasive and well tolerated by patients; it has a potential for colorectal cancer screening.
Key words:  colorectal neoplasms  screening  exfoliated colonocytes test