Caplp, encoded by CAP1, is a basic region-leucine zipper （bZip） transcription factor in Candida albicans. It has been proven to play important roles in both drug resistance and oxidative stress. Within the AP-1 family, Caplp belongs to the same subgroup which also includes Yaplp, Yap2p, and Paplp. The function of Caplp is regulated by a nuclear localization mechanism. In recent years, some target genes of Caplp have been discovered and the differences as well as similarities between Caplp and Yaplp have been revealed. However, the role of Caplp in the drug resistance of Candida albicans still needs to be further investigated. Currently drug resistance and oxidative stress are the 2 focuses in the research of fungal pathogens, making Caplp very important in the future study. The authors have been involved in Caplp research for a long time and this review introduces the current progress in the area