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皱皮木瓜的化学成分研究Ⅱ
杨颖博1,2,李霞1,3,杨琦1,3,吴志军3,孙连娜1*
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(1.第二军医大学药学院生药学教研室,上海 200433;2.吉林农业大学中药材学院,长春 130118;3.第二军医大学长征医院药学部,上海 200003)
摘要:
目的:研究皱皮木瓜的化学成分。方法:利用多种色谱法对皱皮木瓜的化学成分进行系统研究,并根据理化性质和波谱数据进行结构鉴定。结果:从皱皮木瓜的乙酸乙酯萃取部位分离鉴定了9种化合物,分别为绿原酸甲酯(Ⅰ),5-O-咖啡酰基-奎宁酸丁酯(Ⅱ),奎宁酸丁酯(Ⅲ),5-羟甲基-2-糠醛(Ⅳ),三十烷酸(Ⅴ),(-)-表儿茶素(Ⅵ),7,8-二羟基香豆素(Ⅶ),3,4-二羟基苯甲酸乙酯(Ⅷ),原儿茶酸(Ⅸ)。结论:化合物Ⅲ~Ⅷ均为从本属植物中首次分离得到。
关键词:  木瓜属  皱皮木瓜  化学成分
DOI:10.3724/SP.J.1008.2009.01195
投稿时间:2009-04-15修订日期:2009-07-23
基金项目:上海市科委中药现代化专项资助项目(06DZ19715-2).
Studies on chemical constituents of Chaenomeles speciosa (Sweet) Nakai (Ⅱ)
YANG Ying-bo1,2,LI Xia1,3,YANG Qi1,3,WU Zhi-jun3,SUN Lian-na1*
(1.Department of Pharmacognosy,School of Pharmacy,Second Military Medical University,Shanghai 200433,China;2.College of Traditional Herbal Medicine,Jilin Agricultural University,Changchun 130118;3.Department of Pharmacy,Changzheng Hospital,Second Military Medical University,Shanghai 200003)
Abstract:
Objective:To investigate the chemical constituents of Chaenomeles speciosa.Methods: The chemical constituents of Chaenomeles speciosa was analyzed by various chromatographic methods.The structures of the compounds were identified based on physicochemical properties and spectral data.Results: Nine compounds were obtained from the ethyl acetate fraction of C.speciosa and were identified as methyl chlorogenate (Ⅰ),5-O-cafeoyl quinic acid butyl ester (Ⅱ),quinic acid butyl ester (Ⅲ),5-hydroxymethyl-furan-2-carbaldehyde (Ⅳ),triacontanoic acid (Ⅴ),(-)-epicatichin (Ⅵ),7,8-dihydroxy-coumanrin (Ⅶ),protocatechuic acid ethyl ester (Ⅷ),and protocatechuic acid (Ⅸ).Conclusion: Compounds Ⅲ-Ⅷ have been obtained from this genus for the first time.
Key words:  Chaenomeles  Chaenomeles speciosa (Sweet) Nakai  chemical constituent