| 摘要: |
| 近期的研究表明,微小RNA(microRNA,miRNA)作为重要的转录后基因调控元件,在许多脏器的慢性损伤的发生和发展中起着重要作用。本文就近年来miRNA与慢性肝脏损伤的相关研究作一综述。 |
| 关键词: miRNA 慢性脏器损伤 慢性病毒性肝炎 原发性胆汁性肝硬化 肝纤维化 |
| DOI：10.3724/SP.J.1008.2010.0896 |
| 投稿时间：2009-12-12修订日期：2010-05-02 |
| 基金项目: |
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| MicroRNAs and chronic liver disease: recent progress |
| XU Mi-die, LI Wei-qing,,YU Hong-yu |
| (Department of Pathology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China) |
| Abstract: |
| Recent studies have indicated that miRNA is an important element that regulates gene expression at the post transcriptional level. MiRNAs play important roles in development and progression of chronic disorders of many organs. This review summarizes the recent researches on the association of miRNA with chronic liver diseases. |
| Key words: miRNA chronic liver disease chronic viral hepatitis primary biliary cirrhosis hepatic fibrosis |
