湿热环境对晕动病发病的影响
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新药创制重大专项课题(2008ZXJ09009-002).


Effect of high environmental temperature and humidity on incidence of motion sickness
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Supported by New Drugs Creation Special Projects of China(2008ZXJ09009-002).

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    摘要:

    目的观察常温、高温、高温高湿环境下晕动病发病的差异,探讨高温、高湿环境对晕动病发病的影响。方法某大学459名男性学员,18~23岁,体检和体能测试均合格,分别暴露于常温(20℃)、高温(38℃)及高温高湿(38℃/80%湿度)环境下,以科里奥利(Coriolis)加速度转椅试验诱发晕动病,采用格瑞比尔(Graybiel)法评定晕动病程度。结果常温、高温、高温高湿环境下受试者晕动病发病率分别为47.93%、68.94%、100%,格瑞比尔评分分别为2.07±3.12、6.06±5.45、11.87±3.42,高温高湿组显著高于高温组和常温组,差异具有统计学意义(χ2=651.84, P<0.000 1);3种条件下,受试者晕动病发病等级差异亦有统计学意义(χ2=644.73,P<0.000 1)。结论高温高湿环境更容易诱导受试者产生晕动病,并可加重晕动病的症状。

    Abstract:

    ObjectiveTo observe the changes of motion sickness incidences under normal temperature (NT), high environmental temperature(HT), and high environmental temperature/humidity (HTHH), so as to study the influence of high environmental temperature/humidity on the onset of motion sickness. MethodsA total of 459 male students in a university, aged 18-23 years and with normal physical condition/ability, were subjected for Coriolis acceleration test under the condition of 20℃/55%RH (NT), 38℃/55%RH (HT), and 38℃/80%RH (HTHH); then the motion sickness severity was evaluated using Graybiel scale. ResultsThe motion sickness incidences of NT, HT, and HTHH groups were 47.93%, 68.94%, and 100%, and Graybiel scores were (2.07±3.12), (6.06±5.45) and (11.87±3.42), respectively, with the latter significantly higher than those of the former two for Graybiel scores (P<0.000 1). The severity scales of motion sickness were also significantly different between the three groups (P<0.000 1).ConclusionHigh environmental temperature and humidity can accelerate the onset of motion sickness and aggravate the symptoms of motion sickness.

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  • 收稿日期:2010-01-23
  • 最后修改日期:2010-03-14
  • 录用日期:2010-05-19
  • 在线发布日期: 2010-06-24
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