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| 蜂斗菜的化学成分研究 |
| 李余先1,2,3,王燕3,郭美丽3*,郭美丽 |
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| (1.吉林农业大学中药材学院,长春130118; 2.吉林农业科技学院植物科学学院,吉林 132101; 3.第二军医大学药学院生药学教研室,上海 200433) |
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| 摘要: |
| 目的对中药蜂斗菜根茎的化学成分进行分离鉴定。方法用色谱法和波谱法对蜂斗菜根茎的化学成分进行分离鉴定。结果从中分离得到5个化合物:β-谷甾醇(Ⅰ)、麦角甾醇(Ⅱ)、蜂斗菜内酯-B(Ⅲ)、蜂斗菜内酯-D(Ⅳ)、呋喃蜂斗菜醇(Ⅴ)。结论化合物(Ⅱ)为首次从该植物中分离得到。 |
| 关键词: 蜂斗菜 化学成分 结构鉴定 |
| DOI：10.3724/SP.J.1008.2010.0779 |
| 投稿时间：2010-02-02修订日期：2010-03-29 |
| 基金项目:“十一五”科技部重大新药创新专项基金(2009ZX09103-420),上海市科委中药现代化专项基金(08DZ19715). |
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| Study on chemical constituents of Petasites japonicus |
| LI Yu-xian1,2,3 ,WANG Yan3 ,GUO Mei-li3*,GUO Mei-li |
| (1.College of Chinese Herbal Medicine, Jilin Agriculture University, Changchun 130118,Jilin, China; 2.Department of Plant Science, Jilin Agricultural Science and Technology College, Jilin 132101, Jilin, China; 3.Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China) |
| Abstract: |
| eTo isolate and identify the chemical constituents in the rhizome of the Petasites japonicus.MethodsDried rhizome of Petasites japonicus were subjected to extraction with EtOH,and the chemical constituents in the extract were isolated and their structures were identified by physicochemical properties and spectral analysis.ResultsFive compounds were obtained and identified from the rhizome of Petasites japonicus,inlcuding as β-sitoterol(Ⅰ) ,ergosterol (Ⅱ), bakkenolide-B (Ⅲ), bakkenolide-D (Ⅳ) and furanofukinol (Ⅴ).ConclusionCompound(Ⅱ) has been obtained from Petasites japonicus for the first time. |
| Key words: Petasites japonicus chemical constituents structure identification |
