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脑磁图描记联合术中唤醒用于显微镜下切除功能区胚胎发育不良性神经上皮瘤
郭韬,李文玲,武江,赵文清*,康进生,杜亚丽,董长征,岳向勇
0
(河北省人民医院功能神经外科,石家庄 050051)
摘要:
\[摘要\]目的总结脑磁图(magnetoencephalography, MEG)描记与术中唤醒联合应用切除功能区胚胎发育不良性神经上皮瘤(dysembroplastic neuroepithelial tumor,DNT)的经验。方法根据MEG结果大体确定功能区范围,在唤醒麻醉下应用术中皮质电刺激刺激相应区域皮质,明确功能区和DNT边界。在显微镜下切除DNT 4例,观察治疗效果。结果4例患者手术效果良好,无功能区损害。长期随访未出现癫发作及DNT复发。结论联合应用MEG与术中唤醒技术显微镜下切除肿瘤是治疗功能区DNT安全、有效的方法。
关键词:  脑磁图描记术  术中唤醒  胚胎发育不良性神经上皮瘤  功能区
DOI:10.3724/SP.J.1008.2011.0198
投稿时间:2010-07-09修订日期:2011-01-10
基金项目:
Magnetoencephalography and awaking anesthesia in microsurgical resection of dysembryoplastic neuroepithelial tumor in function areas
GUO Tao, LI Wen-ling, WU Jiang, ZHAO Wen-qing*, KANG Jin-sheng, DU Ya-li, DONG Chang-zheng, YUE Xiang-yong
(Department of Functional Neurosurgery, People’s Hospital of Hebei Province, Shijiazhuang 050051, Hebei, China)
Abstract:
\[Abstract\]ObjectiveTo summarize our experience on application of magnetoencephalography (MEG) and awaking anesthesia in microsurgical treatment of dysembryoplastic neuroepithelial tumors in the functional areas.MethodsThe range of the functional area was largely defined by MEG; intraoperative cortical electrical stimulation was used under awaking anesthesia to identify the border of function area and dysembryoplastic neuroepithelial tumors. Dysembryoplastic neuroepithelial tumors were resected under microscope in four patients and the outcomes of the patients were observed.ResultsSatisfactory outcomes were obtained in the 4 patients and there were no injuries in the function area. No epileptic seizures or recurrence of dysembryoplastic neuroepithelial tumors were found during long term follow-up.ConclusionCombined treatment using MEG and awaking anesthesia contributes to safe and effective surgical treatment of dysembroplastic neuroepithelial tumors in the function areas.
Key words:  magnetoencephalography  awaking anesthesia  dysembroplastic neuroepithelial tumor  function area