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  • 温鑫菲,娄淑杰*,邹军.低氧环境下运动对大鼠血清睾酮、皮质酮浓度及其比值的影响[J].第二军医大学学报,2011,32(7):710-713    [点击复制]
  • WEN Xin-fei,LOU Shu-jie*,ZOU Jun.Effect of hypoxia training on serum testosterone(T), corticosterone(C) and T/C value in rats[J].Acad J Sec Mil Med Univ,2011,32(7):710-713   [点击复制]
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低氧环境下运动对大鼠血清睾酮、皮质酮浓度及其比值的影响
温鑫菲,娄淑杰*,邹军
0
(上海体育学院运动科学学院运动生化教研室,上海 200438)
摘要:
目的观察不同低氧浓度环境训练后大鼠血清睾酮(testosterone,T)、皮质酮(corticosterone, C)的浓度及T/C的变化,为确立适宜的低氧训练模式提供实验依据。方法SD大鼠60只,随机分为安静对照组(C)、常氧运动组(E)、15%氧浓度对照组(15C)、15%氧浓度运动组(15E)、11%氧浓度对照组(11C)和11%氧浓度运动组(11E),每组10只,运动方式为跑台运动。采用ELISA方法检测大鼠血清中T和C的浓度。结果(1)11C组T浓度低于C组(P<0.05);11E组T浓度低于
关键词:  低氧训练  睾酮  皮质酮
DOI:10.3724/SP.J.1008.2011.0710
投稿时间:2010-11-18修订日期:2011-05-24
基金项目:国家自然科学基金(30870349)、上海市教委科研创新项目(09yz304)和上海市重点学科建设项目(S30802)
Effect of hypoxia training on serum testosterone(T), corticosterone(C) and T/C value in rats
WEN Xin-fei,LOU Shu-jie*,ZOU Jun
(Department of Sports Biochemistry, School of Sports Science, Shanghai University of Sport, Shanghai 200438, China)
Abstract:
Objective: To observe the change of serum testosterone (T)、serum corticosterone (C) and T/C of in SD rats which have been trained in different hypoxic concentration, and provide a eligible experiment evidence for hypoxia training. Methods: 60 SD rats(8-week-old) were randomly divided into 6 groups which denominated with control (C), exercise(E), 15% control (15C), 15% exercise(15E), 11% control(11C), and 11% exercise(11E) group, the way of exercise is treadmill running , and the level of serum T and C were checked by ELISA. Results: (1) the level of T in group 11C is lower than in group C(P<0.05); the level of T in group 11E is lower than in group E(P<0.01); (2) the level of C in group E is higher than in group C(P<0.05); the level of C in group 11E and 15E are lower than in group E(P<0.05); (3) the ratio of T/C in group 11C is lower than in group C(P<0.05). Conclusion: The 11% oxygen concentration may cause negative effects on the T/C balance, but exercise may compensate the negative effect to some extent; the 15% oxygen concentration not yet influence the T/C balance.
Key words:  hypoxia  training  testosterone  corticosterone  T/C  rat