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| 纳米磷酸钙人工骨应用于经皮椎体后凸成形术的短期临床观察 |
| 吴祥1,徐委2,曾至立2,胡笑2,席波1,周跃峰1,苏佳灿3* |
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(1. 浙江省宁波市小港医院骨科,宁波 315800
2. 同济大学附属同济医院骨科,上海 200065
3. 第二军医大学长海医院骨科,上海 200433
*通信作者) |
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| 摘要: |
| 目的 观察纳米磷酸钙人工骨应用于经皮椎体后凸成形术治疗骨质疏松性椎体压缩性骨折的临床效果。方法 选择33例骨质疏松性胸腰椎压缩性骨折患者,均在全身麻醉下行纳米磷酸钙人工骨单球囊双侧扩张经皮椎体后凸成形术。计算手术后椎体前缘复位率和后凸矫正率,记录术前及术后的疼痛评分，观察术前、人工骨注入时、注入后5 min及术毕的血压、血氧饱和度(SPO2)变化。结果 椎体复位率及后凸矫正率分别为(24.90±3.02)%和(45.80±7.13)%,术后疼痛明显减轻。人工骨注入后血压均较平稳,SPO2在各时点差异无统计学意义(P＞0.05)。结论 纳米磷酸钙人工骨应用于经皮椎体后凸成形术治疗骨质疏松性椎体压缩性骨折安全有效,对患者的生命体征影响较小。 |
| 关键词: 纳米技术 磷酸钙类 人工骨 经皮椎体后凸成形术 治疗结果 |
| DOI：10.3724/SP.J.1008.2012.001151 |
| 投稿时间：2012-05-21修订日期：2012-09-13 |
| 基金项目: |
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| Application of nanometer calcium phosphate ceramic artificial bone in percutaneous kyphoplasty: a short-term clinical observation |
| WU Xiang1,XU Wei2,ZENG Zhi-li2,HU Xiao2,XI Bo1,ZHOU Yue-feng1,SU Jia-can3* |
(1. Department of Orthopaedics, Xiaogang Hospital, Ningbo 315800, Zhejiang, China
2.Department of Orthopaedics, Tongji Hospital, Tongji University, Shanghai 200065, China
3. Department of Orthopaedics, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
*Corresponding author.) |
| Abstract: |
| ObjectiveTo observe the clinical effects of nanometer calcium phosphate ceramic artificial bone (NCPCAB) in percutaneous kyphoplasty for treatment of osteoporotic vertebral compression fractures. MethodsTotally 33 cases of osteoporotic vertebral compression fractures were selected in the present study. All cases were injected with NCPCAB for percutaneous kyphoplasty via bilateral transpedicular balloon approach. Anterior vertebral reset rate and kyphosis correction rate were calculated after treatment. The visual analogue scales (VAS) were observed preoperatively and postoperatively. The changes of blood pressure and SPO2 were observed preoperatively, at injection of the artificial bone, 5 min after injection and at the end of surgery. ResultsThe postoperative vertebra reduction rate and kyphosis correction rate were (24.90±3.02)% and (45.80±7.13)%, respectively. The pain was greatly reduced after operation. The blood pressure was stable after injection of the artificial bone, and SPO2 was not markedly different at each time point. ConclusionApplication of NCPCAB in percutaneous kyphoplasty is safe and effective for treatment of osteoporotic vertebral compression fractures, with little influence on the vital signs of patients. |
| Key words: nanotechnology calcium phosphates artificial bone percutaneous kyphoplasty outcomes |
