| 摘要: |
| 目的 探讨原发性气管髓外浆细胞瘤的临床特征、诊疗方法及预后。 方法 对本院1例及中外文文献报道的9例原发性气管髓外浆细胞瘤病例进行回顾性总结，分析其临床资料。结果 本院病例因“体检发现气管占位”入院，经电子支气管镜检查并行高频圈套治疗，术后病理确诊髓外浆细胞瘤，排除全身其他部位病变后胸外科行手术根治治疗。文献报道的9例患者中症状以呼吸困难（7/9）为主，其次为咳嗽（4/9），咯血（1/9）。8例有胸部CT检查资料，胸部CT检查均可见气管占位，1例系在行甲状腺B超检查时意外发现气管上段前部占位。单纯手术治疗5例；单纯支气管镜下治疗2例，其中1例行硬质支气管镜下切除，1例行腔镜下摘除、基底部灼烧；手术、局部放疗1例；支气管镜下高频圈套、激光、局部放疗1例。7例有较完整的随访资料，随访时间为3月至24月，均未见局部复发及远处转移。 结论 原发性气管髓外浆细胞瘤是一种临床罕见的疾病，确诊需依靠病理及免疫组化结果，目前治疗多以腔镜下摘除或手术切除，术后予以局部放疗为主。 |
| 关键词: 气管 髓外浆细胞瘤 诊断 治疗 |
| DOI： |
| 投稿时间：2013-07-19修订日期：2013-11-09 |
| 基金项目: |
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| Clinical Analysis of Primary Tracheal Extramedullary Plasmacytoma |
| 徐健,li qiang |
| (Department of Respiratory Medicine,Changhai Hospital,Second Military University) |
| Abstract: |
| [abstract] Objective To explore the clinical features、diagnosis and treatment methods and prognosis of the primary tracheal Extramedullary Plasmacytoma. Methods One case of our hospital and nine cases reported in chinese-foreign language were retrospectively summarized and analyzed. Results The case in our hospital was admitted to hospital for tracheal neoplasm , patient was treated by high frequency electrocautery, and pathological findings was Extramedullary Plasmacytoma. The main symptoms of other 9 cases were dyspnea (7/9), cough (4/9) , hemoptysis (1/9). 8 cases were founded tracheal neoplasm by the means of chest CT examination, and 1 case was discovered by means of B ultrasound. 5 cases were Simplely treated by surgery; 2 cases were treated under the bronchoscope : 1 of which under rigid bronchoscope; 1 of which treated by high frequency electrocautery and high frequency electric coagulation under the bronchoscope；1 cases was treated by surgery plus local radiotherapy；1 case was treated by high frequency electrocautery 、laser and local radiotherapy. 7 cases had complete follow-up data for 3 months to 24 months, and no local recurrence and distant metastasis were founded. Conclusion Primary tracheal extramedullary plasmacytoma is a rare clinical disease, diagnosis depends on pathological and immunohistochemical results, and at present the main treatments are remove under the bronchoscope、surgical resection, or postoperative local radiotherapy. |
| Key words: Trachea Extramedullary Plasmacytoma Diagnosis Treatment |
