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| 口服补液为主治疗利比里亚埃博拉病毒病(附4例报告) |
| 陈志辉1,2,李福祥1,3,郝春秋1,4,周飞虎1,5,杨建军1,6,张萍1,7,蔡颖1,8,阴继凯1,9,郭万刚1,10,郭昌星1,11,李成忠1,2* |
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(1. 中国人民解放军第二批援利医疗队;
2. 第二军医大学长海医院感染科, 上海 200433;
3. 成都军区总医院重症医学科, 成都 610083;
4. 第四军医大学唐都医院传染科, 西安 710038;
5. 解放军总医院重症医学科, 北京 100853;
6. 成都军区昆明总医院传染结核科, 昆明 650032;
7. 成都军区昆明总医院急诊科, 昆明 650032;
8. 解放军324医院感染性疾病科, 重庆 400020;
9. 第四军医大学唐都医院普通外科, 西安 710038;
10. 第四军医大学唐都医院心内科, 西安 710038;
11. 第二军医大学长征医院急救科, 上海 200003
*通信作者) |
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| 摘要: |
| 目的 探讨口服补液盐为主治疗埃博拉病毒病的疗效。方法 分析在利比里亚治疗的4例埃博拉病毒病患者的治疗结果。根据病情轻重和是否伴有严重呕吐来确定采用口服或静脉补液,依据个体情况包括尿量、粪便量和排汗量等确定用量,每天补液750~2 000 mL。其中3例采用口服补液,另1例第1天采用口服补液,后因病情较重改为静脉补液。疗程到临床症状完全缓解。结果 主要接受口服补液治疗的3例埃博拉病毒病的患者痊愈,接受静脉输液治疗的1例死亡。结论 口服补液应作为早期、长期、就地治疗经济、卫生状况落后的西非地区轻、中度埃博拉病毒病的一线措施。 |
| 关键词: 埃博拉病毒病 补液疗法 口服补液盐 治疗结果 |
| DOI：10.3724/SP.J.1008.2015.00590 |
| 投稿时间：2015-04-01修订日期：2015-05-20 |
| 基金项目: |
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| Oral rehydration therapy of Ebola virus disease in Liberia: a report of 4 cases |
| CHEN Zhi-hui1,2,LI Fu-xiang1,3,HAO Chun-qiu1,4,ZHOU Fei-hu1,5,YANG Jian-jun1,6,ZHANG Ping1,7,CAI Ying1,8,YIN Ji-kai1,9,GUO Wan-gang1,10,GUO Chang-xing1,11,LI Cheng-zhong1,2* |
(1. The Second Medical Team of the Chinese People's Liberation Army to Liberia;
2. Department of Infectious Diseases, Changhai Hospital, Second Military Medical University, Shanghai 200433, China;
3. Department of Critical Care Medicine, General Hospital, PLA Chengdu Military Area Command, Chengdu 610083, Sichuan, China;
4. Department of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, Shaanxi, China;
5. Department of Intensive Care Medicine, PLA General Hospital, Beijing 100853, China;
6. Department of Infectious Diseases and Tuberculosis, Kunming General Hospital, PLA Chengdu Military Area Command, Kunming 650032, Yunnan, China;
7. Department of Emergency, Kunming General Hospital, PLA Chengdu Military Area Command, Kunming 650032, Yunnan, China;
8. Department of Infectious Diseases, No. 324 Hospital of PLA, Chongqing 400020, China;
9. Department of General Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, Shaanxi, China;
10. Department of Cardiovasology, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, Shaanxi, China;
11. Department of Emergency, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
*Corresponding authors) |
| Abstract: |
| Objective To investigate the effect of oral rehydration salts for treating Ebola virus disease. Methods The treatment outcomes of 4 patients with confirmed Ebola virus disease in Liberia were analyzed. Oral or intravenous rehydration salts were chosen according to the severity of illness and the occurrence of severe vomiting. The fluid volume was determined according to the following conditions: urine, feces and sweat volume, and the daily fluid volume was 750-2 000 mL. Three patients received oral rehydration salts; one patient received oral rehydration salts on the first day and intravenous rehydration salts afterwards due to severe illness. The rehydration salt treatment was given until the complete remission of clinical symptoms. Results The three patients receiving oral rehydration treatment survived and the severe case who also received intravenous treatment died finally. Conclusion Oral rehydration should be used as the first-line choice for early, long-term treatment of patients with mild to moderate Ebola virus disease in West Africa, where the economic and health situation are backward. |
| Key words: Ebola virus disease fluid therapy oral rehydration salts treatment outcome |
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