| 摘要: |
| 新型冠状病毒肺炎（COVID-19）除损伤呼吸系统外，还可累及神经系统，甚至造成严重的临床后果。本文从致病机制、临床症状及治疗预后3个方面阐述了严重急性呼吸综合征冠状病毒2（SARS-CoV-2）对神经系统损伤的研究现状，系统性归纳了COVID-19神经系统病变的病理机制，为COVID-19的诊断和治疗提供新思路。 |
| 关键词: 严重急性呼吸综合征冠状病毒2 病理机制 神经系统损害 临床特征 诊断 治疗 |
| DOI：10.16781/j.CN31-2187/R.20210777 |
| 投稿时间：2021-08-09修订日期：2021-09-29 |
| 基金项目:国家自然科学基金(81872072). |
|
| Nervous system injury caused by severe acute respiratory syndrome coronavirus 2:research status |
| MA Pei-pei1,HONG Fan1,XU Tao1,CHEN Ju-xiang2* |
(1. Department of Neurosurgery, The Second Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200003, China;
2. Department of Neurosurgery, The First Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200433, China
*Corresponding author) |
| Abstract: |
| In addition to damaging the respiratory system, coronavirus disease 2019 (COVID-19) can also affect the nervous system, and even cause serious clinical consequences. This paper expounds the research status of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on nervous system injury from 3 aspects: pathogenesis, clinical symptoms and treatment prognosis, and systematically summarizes the pathological mechanism of nervous system lesions caused by COVID-19, hoping to provide new ideas for the diagnosis and treatment of COVID-19. |
| Key words: severe acute respiratory syndrome coronavirus 2 pathological mechanism nervous system damage clinical features diagnosis therapy |
