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| 大血管闭塞急性缺血性脑卒中超时间窗机械取栓研究现状 |
| 张小曦,花伟龙,沈红健,张磊,张永鑫,邢鹏飞,李子付,张永巍,杨鹏飞*,刘建民 |
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(海军军医大学(第二军医大学)长海医院脑血管病中心, 上海 200433
*通信作者) |
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| 摘要: |
| 血管再通治疗是大血管闭塞急性缺血性脑卒中（AIS-LVO）最主要的治疗方式。研究证实AIS-LVO机械取栓的明确时间窗为发病6 h内，对于发病6~24 h或超过24 h接受机械取栓的患者筛选仍存争议。本文对发病或末次正常时间为6~24 h的超时间窗AIS-LVO患者和超出24 h的超晚期AIS-LVO患者的机械取栓治疗现状进行总结，并分析延长取栓时间窗的可行性和评估策略。 |
| 关键词: 急性缺血性脑卒中 超时间窗 大血管闭塞 机械取栓术 |
| DOI：10.16781/j.0258-879x.2022.01.0009 |
| 投稿时间：2021-09-20 |
| 基金项目:中国脑卒中高危人群干预适宜技术研究及推广项目（GN-2020R0008），上海市扬帆计划（20YF1448000），上海市临床重点专科项目（shslczdzk06101），海军军医大学（第二军医大学）长海医院青年启动基金（2018QNA007） |
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| Mechanical thrombectomy for acute ischemic stroke with large vessel occlusion beyond time window: current status |
| ZHANG Xiao-xi,HUA Wei-long,SHEN Hong-jian,ZHANG Lei,ZHANG Yong-xin,XING Peng-fei,LI Zi-fu,ZHANG Yong-wei,YANG Peng-fei*,LIU Jian-min |
(Neurovascular Center, Changhai Hospital, Naval Medical University (Second Military Medical University), Shanghai 200433, China
*Corresponding author) |
| Abstract: |
| Vascular recanalization therapy is the major treatment strategy for acute ischemic stroke with large vessel occlusion (AIS-LVO). Time window for mechanical thrombectomy has been proven to be within 6 h after stroke onset. Screening of patients who are to undergo mechanical thrombectomy 6-24 h or beyond 24 h after onset remains controversial. In this review, we summarize the current status of mechanical thrombectomy in AIS-LVO patients with extended time window of 6-24 h or beyond 24 h, and analyze the feasibility and evaluate the strategies for extending the time window of thrombectomy. |
| Key words: acute ischemic stroke beyond time window large vessel occlusion mechanical thrombectomy |
