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氦氧混合气在医学实践中的应用
贾路恒1,2,张坤2,王晔炜2,朱包良2,庆龙2,周英杰2,徐伟刚1,2*
0
(1. 上海理工大学健康科学与工程学院, 上海 200093;
2. 海军军医大学(第二军医大学)海军特色医学中心, 上海 200433
*通信作者)
摘要:
氦氧混合气是由氦气与氧气按照一定比例混合制成,传统上主要用作大深度潜水作业的呼吸气体。近年来,氦氧混合气因能降低呼吸阻力、提高组织氧含量、抑制炎症反应等,被进一步用于呼吸系统疾病、缺血性疾病和减压病等的预防和治疗。未来随着对氦氧混合气研究的持续深入,其应用将不断拓展。本文从理化性质、疾病防治、治疗方案、风险控制4个方面系统介绍氦氧混合气在医疗实践中的应用,为后续相关研究提供借鉴。
关键词:  氦氧混合气  呼吸道疾病  缺血性疾病  氦氧潜水  减压病
DOI:10.16781/j.CN31-2187/R.20220349
投稿时间:2022-04-27修订日期:2022-07-01
基金项目:
Application of heliox in medical practice
JIA Luheng1,2,ZHANG Kun2,WANG Yewei2,ZHU Baoliang2,QING Long2,ZHOU Yingjie2,XU Weigang1,2*
(1. School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China;
2. Naval Medical Center, Naval Medical University (Second Military Medical University), Shanghai 200433, China
*Corresponding author)
Abstract:
Heliox is a mixture of helium and oxygen in a certain proportion. Traditionally, it is mainly used as respiratory gas in deep diving operations. In recent years, heliox has been used in the prevention and treatment of respiratory diseases, ischemic diseases, and decompression sickness because it can reduce respiratory resistance, increase tissue oxygen content, and inhibit inflammatory response. In the future, with in-depth study of heliox, its application will continue to widen. This article systematically introduces the application of heliox in medical practice from 4 aspects: physical and chemical properties, disease prevention and treatment, treatment methods, and risk control, hoping to provide a reference for further research.
Key words:  heliox  respiratory diseases  ischemic diseases  helium-oxygen diving  decompression sickness