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血管内光学相干断层成像在脑血管疾病介入诊疗中的应用进展
许燕1,2,李子付2,赵瑞2*
0
(1. 上海理工大学健康科学与工程学院, 上海 200093;
2. 海军军医大学(第二军医大学)第一附属医院脑血管病中心, 上海 200433
*通信作者)
摘要:
光学相干断层成像(OCT)是一种基于红外线进行组织成像的技术,可实现高达 10~20 μm 的分辨率,已被广泛应用于冠状动脉病变诊疗,在脑血管疾病的诊疗中也日益受到重视。OCT 在颈动脉狭窄、颅内动脉狭窄及夹层、脑动脉瘤和脑静脉疾病介入诊疗中的应用已经取得了一些进展,但目前尚缺乏大样本数据的循证支持。由于脑血管具有独特的解剖特点,需要寻求更为合适的器械设计。通过不断的器械改进和技术进步, OCT 有望成为脑血管疾病预防、诊断和治疗的重要影像功能检测工具。
关键词:  光学相干断层成像  脑血管疾病  介入治疗  应用
DOI:10.16781/j.CN31-2187/R.20230552
投稿时间:2023-10-07修订日期:2024-01-18
基金项目:国家重点研发计划(2023YFC2412804).
Application of intravascular optical coherence tomography in interventional diagnosis and treatment of cerebrovascular diseases: recent progress
XU Yan1,2,LI Zifu2,ZHAO Rui2*
(1. School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China;
2. Neurovascular Center, The First Affiliated Hospital of Naval Medical University(Second Military Medical University), Shanghai 200433, China
*Corresponding author)
Abstract:
Optical coherence tomography (OCT) is a tissue imaging based on infrared ray, and it can achieve a resolution up to 10-20 μm. It has been widely used in the diagnosis and treatment of coronary artery diseases, and its applications in the diagnosis and treatment of cerebrovascular diseases have also been increasingly valued. The applications of OCT in interventional diagnosis and treatment of carotid artery stenosis, intracranial artery stenosis and dissection, cerebral aneurysms and cerebral venous diseases have made some progress, but there is still a lack of robust large-sample evidence. Due to the unique anatomical features of cerebral vessels, there is a need for more suitable instrument designs. With the continuous improvement in instrument designs and techniques, OCT is expected to become a crucial imaging tool for the prevention, diagnosis, and treatment of cerebrovascular diseases.
Key words:  optical coherence tomography  cerebrovascular diseases  interventional therapy  application