Objective：To investigate the blood pressure, heart rate and metabolism status in disabled Uigur subjects in rural district of Kuerle, Xinjiang Autonomous Region, so as to provide a basis for health care of the disabled. Methods: The systolic pressure (SBP), diastolic pressure (DBP), heart rate (HR), body mass index, waist circumference, fasting plasma glucose, total cholesterol (TC), and triglycerides (TG) were determined in 120 disabled subjects (64 males, 56 females) and 126 normal individuals (60 males, 66 females). The results were compared between the disabled and the normal subjects. Results: Blood pressure was significantly lower in the disabled than in normal individuals (male SPB: \[117±19\] mmHg vs \[125±23\] mmHg（1 mmHg=0.133 kPa）, P<0.05, DBP: \[74±13\] mmHg vs \[79±12\] mmHg, P<0.05; female SPB: \[117±21\] mmHg vs \[126±22\] mmHg, P<0.05, DBP: \[74±11\] mmHg vs \[80±13\] mmHg, P<0.05). HR was significantly higher in the male disabled than in male normal individuals (\[86±13\] beat/min vs \[79±11\] beat/min, P<0.05). TC and TG were lower in the female disabled than in the female normal individuals (TC: \[4.0±0.6\] mmol/L vs \[4.4±0.6\] mmol/L, P<0.05; TG: \[1.1±0.4\] mmol/L vs \[1.5±0.5\] mmol/L, P<0.05\] ; there were no significant difference in the males (P>0.05). Fasting plasma glucose was not significantly different between the disabled and the normal individuals (P>0.05). A stepwise multiple linear regression analysis showed that age and waist circumference were independent predictors of blood pressure; disability and waist circumference were significant independent predictors of HR. Conclusion: Blood pressure is lower in the disabled Uigurs of both sexes; HR is higher in the disabled male and blood lipid is lower in the disabled female in rural district of Kuerle of Xinjiang Autonomous Region.