A goat model for research of anterior cervical-adjustable fusion fixator
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    Abstract:

    Objective:To establish an animal model for anterior cervical-adjustable fusion fixator (AC-AFF),and to compare the operation time,blood loss,and recovery time of food intake and movement between AC-AFF group and other groups with different cervical reconstruction fixators.Methods: Eighteen goats were evenly randomized into 3 groups: AC-AFF,steel plate+titanium mesh,and steel plate+autogenous iliac bone group.The 3 fixtors were implanted after corpectomy.The operation time,blood loss during operation,and recovery time of food intake and movement were recorded in each animal and were compared.Results: All experiment animals survived after operation; one animal of steel plate+titanium mesh group suffered from incision infection and recovered 5 days after intramuscular penicillin therapy.Two animals in steel plate+autogenous iliac bone group could not stand on forehoof,but food intake was not influenced; the animals could stand 1 week later without treatment and walked with difficulty,and they recovered normal walk 2 weeks later.Four animals received C3 corpectomy (2 received AC-AFF and 2 received steel plate+titanium mesh) and the rest received C4 corpectomy.It was found that AC-AFF group had the shortest operation time (P<0.01),and there was no difference between the other 2 groups.The intra-operation blood loss in the steel plate+autogenous iliac bone group was significantly higher than that in the other 2 groups (P<0.01),with no significant difference found between the latter 2 groups.Conclusion: AC-AFF is easier to manage than the other 2 fixators; besides,AC-AFF has less blood loss,short operation time,less post-operation complication,and early recovery of food intake and movement.

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History
  • Received:October 30,2007
  • Revised:January 07,2008
  • Adopted:January 10,2008
  • Online: March 17,2008
  • Published:
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