Principal component analysis of geographic influence on adult lung compliance
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Supported by National Natural Science Foundation of China(40671005).

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    Abstract:

    Objective:To study the relationship between the lung compliance and the geographic factor in healthy Chinese adults,so as to provide scientific evidence for establishing the standard value of lung compliance for healthy Chinese adults.Methods and Results: We colleted the lung compliance data from 4 489 (2 726 males,1 763 females)healthy adult Chinese from 46 cities and counties across China.The relationship between lung compliance data and geographic factors (altitude\[X1\],annual sunshine duration\[X2\],annual mean air temperature\[X3\],annual mean relative humidity\[X4\],and annual precipitation \[X5\]) were assessed by correlative analysis and co-linearity diagnostics.Then we analyzed the relationship between the reference value and the geographical factors by using the method Principal Component Analysis.The regression equation was:=0.079-0.000 001 66X1-0.000 032 3X2-0.002 21X3+0.001 47X4-0.000 017 4X5±0.021.Conclusion: If geographical factors of an area are obtained,the reference value range of healthy adult lung compliance of this area can be calculated by using the regression equation.

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History
  • Received:June 05,2008
  • Revised:November 02,2008
  • Adopted:January 16,2009
  • Online: January 16,2009
  • Published:
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