Objective:To explore the application and efficiency of unilateral vertebral plate decompression,interbody fusion and pedicle screw fixation in treatment of lumbar disc herniation. Methods:From Feb. 2006 to Feb. 2008,24 patients underwent unilateral vertebral plate decompression,interbody fusion and pedicle screw fixation. The patients were followed up for one year and the following data were recorded:operation time,estimated blood loss,duration of hospital-stay,short-term and medium-term clinical outcome. Results:All patients had their low back pain and/or lower extremity radicular pain improved during the one year follow-up. The last follow-up showed that the numbers of patients with Oswestry Disability Index(ODI) P0-P5 were 5,11,6,2,0,and 0,respectively. The clinical outcomes determined by modified JOA criteria showed that 18 patients had excellent outcomes,4 had good outcomes,and 2 had fair outcomes,with the excellent and good outcomes occupying 91.67%. Conclusion:The unilateral fixation can be used in patients with lumbar disc herniations who need lumbar spinal fusion. The medium-term outcomes is satisfactory.