Objective:To observe the manifestations of magnetic resonance cholangiopanceatography (MRCP) and conventional magnetic resonance imaging (MRI) for pancreaticobiliary duct lesions. Methods: Fifty-eight patients with pancreaticobiliary duct lesions,which were confirmed by pathology and comprehensive imaging,were examined by 3D-MRCP volume scanning with thin slice reconstruction,2D-MRCP projective scanning and conventional MRI. The MRCP and MRI manifestations of different lesions were analyzed and their diagnostic values were discussed. Results: Calculus of bile duct and pancreatic duct was found in 28 patients,chronic pancreatitis in 9,pancreatic cancer in 9,carcinomas of bile duct in 5,metastases to lymph nodes of porta hepatic in 2,congenital choledochus dilatation,cholecystectomy,pancreas divisum,post liver transplantation,and malignant intraductal papillary mucinous tumor of pancreatic duct all in 1. The manifestations of 3D-MRCP volume scanning with thin slice reconstruction,2D-MRCP projective scanning and conventional MRI for pancreaticobiliary duct lesions were different and had their own characteristics. Conclusion: The combinations of 3D-MRCP volume scanning with thin slice reconstruction,2D-MRCP projective scanning and conventional MRI can help to locate and diagnose pancreaticobiliary duct lesions.