\[Abstract\]ObjectiveTo analyze the risk factors of emergence agitation in patients with hepatobiliary diseases. MethodsA total of 110 patients with hepatobiliary disease were enrolled in the present study. The level of emergence agitation was scored by sedation-agitation scale (SAS) 30 min after the surgery. Patients with SAS < 4, were excluded. Related medical data of the rest 90 patients were subjected to univariate and multivariate Logistic regression for analysis of risk factors of emergence agitation. ResultsUnivariate analysis revealed that the airway management method, anesthesia maintenance method, operation time and the use of anesthetic gas absorber were significantly correlated with the incidence of agitation (P values being 0.014, 0.011, 0.042 and 0.019, respectively). Multivariate analysis revealed that induction with midazolam, urinary catheterization after anesthesia and total inhalational anesthesia were significantly correlated with the incidence of agitation (P values being 0.026, 0.049 and 0.004, and the OR values being 5.481, 10.867, and 11.604, respectively). ConclusionIn patients with hepatobiliary diseases, induction with midazolam, total inhalational anaesthesia and urinary catheterization after anesthesia are associated with high incidence of emergence agitation following general anaesthesia.